new bone cements with pluronic

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New bone cements with Pluronic®F127 for prophylaxis and ...

New bone cements with Pluronic®F127 for prophylaxis and treatment of periprosthetic joint infections J Mech Behav Biomed Mater. 2021 Mar 29;119:104496. doi: 10.1016/j.jmbbm.2021.104496. Online ahead of print. Authors Kutsi Tuncer 1 ...

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New bone cements with Pluronic®F127 for prophylaxis and ...

Jul 01, 2021  According to our results, it was suggested that the new PMMA bone cement prepared by adding Pluronic®F127 is applicable for in-vitro studies. Porosity is a desired condition in terms of antibiotic release in the bone cement, but it is undesirable in terms of the mechanical properties and the cement strength.

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New bone cements with Pluronic®F127 for prophylaxis and ...

It was shown that drug release time was increased with Pluronic®F127 polymer-added bone cement. • It was demonstrated by SEM and BET studies that Pluronic®F127 polymer additive changed the pore structure of cement. • Pluronic®F127 polymer additives were demonstrated by four-point bending tests that increased the strength of bone cement.

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Antibiotic-eluting hydrophilized PMMA bone cement with ...

The compressive strengths of the bone cements with Pluronic F68 compositions less than 7 wt% were not significantly different compared with the control vancomycin-loaded bone cement (VAcement). TheF68 (7 wt%)-VAcement showed sustained release of the antibiotic for up to 11 weeks and almost 100% release from the bone cement.

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Abr 3, 2021 – Infectoforum

Apr 03, 2021  New bone cements with Pluronic®F127 for prophylaxis and treatment of periprosthetic joint infections In line with the increase in orthopedic prosthetic surgeries, there has been a significant rise in periprosthetic joint infections (PJI) due to Methicillin

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Antibiotic-eluting hydrophilized PMMA bone cement with ...

Feb 03, 2016  The compressive strengths of the bone cements with Pluronic F68 compositions less than 7 wt% were not significantly different compared with the control vancomycin-loaded bone cement (VA cement). The F68 (7 wt%)-VA cement showed sustained release of the antibiotic for up to 11 weeks and almost 100% release from the bone cement.

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Multifunctional Pluronic P123/F127 mixed polymeric ...

New bone cements with Pluronic®F127 for prophylaxis and treatment of periprosthetic joint infections. 2021, Journal of the Mechanical Behavior of Biomedical Materials. Show abstract.

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Brushite foams the effect of Tween® 80 and Pluronic® F‐127 ...

Abstract: Resorbable calcium phosphate based bone void fillers should work as temporary templates for new bone formation. The incorporation of macropores with sizes of 100 2300 mm has been shown to increase the resorption rate of the implant and speed up bone ingrowth. In this work, macroporous brushite cements were fabricated

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Brushite foams - The effect of Tween® 80 and Pluronic® F ...

Resorbable calcium phosphate based bone void fillers should work as temporary templates for new bone formation. ... the field of brushite cements as bone replacing material. ... of both Pluronic ...

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Journal of the Mechanical Behavior of Biomedical Materials ...

New bone cements with Pluronic®F127 for prophylaxis and treatment of periprosthetic joint infections. Kutsi Tuncer, Bahri Gür, Onur Şenol, Muhammet Raci Aydın, Ömer Gündoğdu. Article 104496 Download PDF. Article preview.

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For Peer Review

bone ingrowth. In this work, macroporous brushite cements were fabricated through foaming of the cement paste, utilizing two different synthetic surfactants, Tween® 80 and Pluronic® F-127. The macropores formed in the Pluronic samples were both smaller and less homogeneously distributed compared with the pores formed in the Tween samples.

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Production and characterization of new calcium phosphate ...

Apr 01, 1999  Production and characterization of new calcium phosphate bone cements in the CaHPO4-alpha-Ca3(PO4)2 system: pH, workability and setting times. E Fernández Dpt. Materials Science and Metallurgy, Universitat Politècnica de Catalunya,

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Self-hardening and thermoresponsive alpha tricalcium ...

Feb 01, 2017  The incorporation of pluronic F127 leads to an increase in the injectability of the cement from 60.5 ± 0.8% for CPC 0% PLU to 98.1 ± 1.2% for the thermoresponsive cement (CPC 20% PLU) irrespective of the temperature of the paste, which can be considered as a total injection due to a small quantity of paste remaining inside the syringe cannula ...

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Brushite foams—the effect of Tween® 80 and Pluronic® F‐127 ...

Jan 01, 2016  Resorbable calcium phosphate based bone void fillers should work as temporary templates for new bone formation. The incorporation of macropores with sizes of 100 −300 µm has been shown to increase the resorption rate of the implant and speed up bone ingrowth. In this work, macroporous brushite cements were fabricated through foaming of the cement paste, using two

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Self-hardening and thermoresponsive alpha tricalcium ...

The thermoresponsive cement exhibited excellent cohesion and clinically acceptable setting times at 37°C, irrespective of the initial temperature of the paste. The addition of pluronic F127 slightly delayed the setting reaction in the early stages but did not hinder the full

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Marc Bohner RMS Foundation - Academia

With Biobon the cement area decreased slower between 2 and 24 weeks, and the new bone formation was less. Both cements were well integrated into the bone in long bones. chronOS-Inject demonstrated good biocompatibility and was almost completely replaced through bone within 24 weeks.

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Brushite foams—the effect of Tween® 80 and Pluronic® F‐127 ...

Jan 23, 2015  The incorporation of macropores with sizes of 100 −300 µm has been shown to increase the resorption rate of the implant and speed up bone ingrowth. In this work, macroporous brushite cements were fabricated through foaming of the cement paste, using two different synthetic surfactants, Tween® 80 and Pluronic® F‐127.

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‪BAHRİ GÜR‬ - ‪Google Scholar‬

‪Associate Professor, Physical chemistry, Iğdır University.‬ - ‪‪Cited by 254‬‬ - ‪Thin films‬ - ‪Graphene oxide‬ - ‪Biosensors‬ - ‪MD Simulations‬ - ‪Supercapacitors‬

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1. Introduction

Yang et al. [118] used calcium phosphate cement (CPC) and IONPs to prepare a new type of scaffold and explored the effect of the new composite material on the formation and bone formation of human dental pulp stem cells (hDPSC). They found that the addition of IONPs greatly promote the bone formation of hDPSC, enhanced mechanical strength and ...

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Antibiotic-eluting hydrophilized PMMA bone cement with ...

Feb 03, 2016  The compressive strengths of the bone cements with Pluronic F68 compositions less than 7 wt% were not significantly different compared with the control vancomycin-loaded bone cement (VA cement). The F68 (7 wt%)-VA cement showed sustained release of the antibiotic for up to 11 weeks and almost 100% release from the bone cement.

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Multifunctional Pluronic P123/F127 mixed polymeric ...

New bone cements with Pluronic®F127 for prophylaxis and treatment of periprosthetic joint infections. 2021, Journal of the Mechanical Behavior of Biomedical Materials. Show abstract.

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Bone regeneration capacity of magnesium phosphate cements ...

The results showed cement degradation in concert with new bone formation at both defect locations. Both cements were almost completely degraded after 10 months. The struvite cement formed with a PLR of 2.0 g ml -1 exhibited a slightly accelerated degradation kinetics compared to the cement with a PLR of 3.0 g ml -1 .

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Influence of magnesium particles and Pluronic F127 on ...

Dec 01, 2018  To get an injectable nanocomposite cement required amount of CSH powder (see Table 1) and nHA and magnesium particles were dispersed in freshly prepared 0.7 mL of 1% Pluronic F127 solution and mixed by magnetic stirring at room temperature to get a homogeneous paste.This paste was immediately transferred to a 5 mL standard plastic syringe to get an injectable nanocomposite bone

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Antibiotic-eluting hydrophilized PMMA bone cement with ...

Feb 03, 2016  Osteomyelitis is still considered to be one of the major challenges for orthopedic surgeons despite advanced antiseptic surgical procedures and pharmaceutical therapeutics. In

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Hyaluronic acid facilitates bone repair effects of calcium ...

Apr 08, 2021  Hematoxylin-eosin staining (HE staining) of the bone tissue with implanted cements for 4 (a), 8 (b) and 12 weeks (b); and Masson's trichrome staining (MST) of the bone tissue with implanted cements for 4 (c), 8 (d) and 12 weeks (e), dense calcified new bone was stained red, while collagen-rich tissues were stained blue, black scale bar at 200 ...

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Brushite foams - the effect of Tween® 80 and Pluronic® F ...

The incorporation of macropores with sizes of 100 -300 µm has been shown to increase the resorption rate of the implant and speed up bone ingrowth. In this work, macroporous brushite cements were fabricated through foaming of the cement paste, utilizing two different synthetic surfactants, Tween® 80 and Pluronic® F-127.

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Flow Behavior and Drug Release Study of Injectable ...

Oct 24, 2019  Furthermore, injectable cements composed of borate-based bioactive glasses represent a new class of bone substitutes . Previous study of Cui et al. [ 34 ] revealed that by controlling the reaction between the borate bioactive glass particles and the chitosan solution, injectable cements can be created with the desired flowability, degradation ...

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Influence of adding Pluronic F127 in the electrolyte on ...

Feb 04, 2021  Abstract In this work, we have investigated the addition of Pluronic F127 (PF127) into the electrolyte solution on the structure, morphology and antibacterial growth of calcium phosphate (CaP) coatings synthesized by an electrochemical method on Ti substrate. Different parameters of the deposition process were investigated, which were temperature, time and PF127 wt%. The coatings

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Bone Cement Failure - Side Effects, Symptoms, Lawsuits

Bone cement may also cause a condition known as bone cement implantation syndrome (BCIS). BCIS is a serious medical condition in which fat, bone marrow, and cement may leak into the bloodstream. When this occurs, patients may suffer from blood clots, pulmonary embolism, cardiac arrest, and other serious adverse events.

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A novel liposomal drug delivery system for PMMA bone cements

Aug 10, 2015  INTRODUCTION. Polymethyl methacrylate (PMMA) bone cements have been widely employed in hip and knee replacements since their introduction by Sir John Charnley in 1953. 1, 2 3 Bone cement has several roles: to secure the implant in place; to distribute stresses between the stiff metallic implant and the bone; and, frequently, to prevent infection by releasing an antibiotic. The

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(PDF) Amphotericin B Delivery From Bone Cement Increases ...

Jun 03, 2011  New bone cements with Pluronic®F127 for prophylaxis and treatment of periprosthetic joint infections. ... Antimicrobial-loaded bone cement made in the proportions of

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Brushite foams—the effect of Tween® 80 and Pluronic® F‐127 ...

Jan 23, 2015  The incorporation of macropores with sizes of 100 −300 µm has been shown to increase the resorption rate of the implant and speed up bone ingrowth. In this work, macroporous brushite cements were fabricated through foaming of the cement paste, using two different synthetic surfactants, Tween® 80 and Pluronic® F‐127.

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A novel liposomal drug delivery system for PMMA bone cements.

Aug 10, 2015  INTRODUCTION. Polymethyl methacrylate (PMMA) bone cements have been widely employed in hip and knee replacements since their introduction by Sir John Charnley in 1953.1, 2 In England and Wales ~178,000 hip and knee replacements, of which 102,700 were cemented, were performed in 2012, a 300% increase since 2004.3 Bone cement has several roles: to secure the

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